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Search Results for " Mycobacterium tuberculosis "

ターゲット

141

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T38359	Dup-721		Antibacterial
	DuP-721 is a broad spectrum and orally active antibacterial agent. DuP-721 inhibits a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis.		Antibacterial
T7342	BM212		Antibacterial
	BM212 is an antimycobacterial compound.It inhibits the growth of laboratory and clinical isolate M. tuberculosis strains.		Antibacterial
T10411	AU1235		Antibacterial
			Antibacterial
T9734	InhA-IN-2		CDK
	InhA-IN-2 directly inhibits InhA and does not require activation by the catalase peroxidase KatG.		CDK
T8694	ML406		Antibacterial , Antibiotic
	ML406 shows anti-tubercular activity via MtbbioA (DAPA synthase) enzyme inhibition(IC50 : 30 nM)		Antibacterial , Antibiotic
T5315	TCA1	TCA-1,TCA 1	Antibacterial , Antibiotic
	TCA1 (TCA 1) is a small molecule with activity against drug-resistant and persistent tuberculosis.		Antibacterial , Antibiotic
T0827	Cefsulodin sodium	Cefsulodine sodium,Sulcephalosporin	Antibacterial , Antibiotic
	Cefsulodin sodium (Sulcephalosporin) hydrate is a β lactam antibiotic.		Antibacterial , Antibiotic
T77730	QST4		Antifungal
	QST4 possessed antitubercular and antifungal activities with a MIC value of 6.25 μM in Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv.		Antifungal
T72576	Transketolase-IN-4		Antibacterial
	Transketolase-IN-4 is a transketolase inhibitor with an IC50 value of 3.9 μM.Transketolase-IN-4 inhibited Mycobacterium tuberculosis DXS with an IC50 value of 114.1 μM. Transketolase-IN-4 inhibited the SW620, LS174T, and...		Antibacterial
T60073	Antimycobacterial agent-4	4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide	Antibacterial
	Antimycobacterial agent-4 (4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide) has antibacterial activity against Mycobacterium tuberculosis.		Antibacterial
T9830	GSK2556286	GSK286	Antibacterial
	GSK2556286 (GSK286) is an orally active inhibitor of Mycobacterium tuberculosis (M. tuberculosis).GSK2556286 inhibits the growth of human macrophages with an IC50 value of 0.07 μM.GSK2556286 is effective against both mul...		Antibacterial
T61411	InhA-IN-4		Antibacterial
	InhA-IN-4 (TU14) is a potent Mycobacterium tuberculosis InhA (enoyl ACP reductase) inhibitor with potential anticancer and antiproliferative activities for the study of Mycobacterium tuberculosis infections.		Antibacterial
T77683	Methyl quinoline-2-carboxylate	Methyl 2-quinolinecarboxylate	Antibacterial
	Methyl quinoline-2-carboxylate (Methyl 2-quinolinecarboxylate) inhibits the binding of Mycobacterium tuberculosis.		Antibacterial
T60866	InhA-IN-3		Antibacterial
	InhA-IN-3 (TU13) is a potent inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase) with potential anticancer and antiproliferative activities for the study of Mycobacterium tuberculosis infections.		Antibacterial
T27453	GSK1733953A	DG70	Antibacterial
	GSK1733953A can be used as a small molecule Mycobacterium tuberculosis respiration inhibitor with an inhibitory effect on MenG activity and an IC50 value of 2.6 ± 0.6 μM.GSK1733953A is a selective biphenylbenzamide with ...		Antibacterial
T3642	TBA-354	TBA 354	Antibacterial , Antibiotic
	TBA-354 is anti-tuberculous and active against Mycobacterium tuberculosis strain H37Rv.		Antibacterial , Antibiotic
T67827	Urease Inhibitor 07		Others
	Urease Inhibitor 07 is an isosubstituted metalloproteinase inhibitor with potential activity against Mycobacterium tuberculosis strain H37Rv.		Others
T2585	Bedaquiline	R207910,TMC207	Antibacterial , Antibiotic
	Bedaquiline (R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.		Antibacterial , Antibiotic
T78745	Mtb-IN-2		Antibiotic
	Mtb-IN-2 is a small molecule compound of Mycobacterium tuberculosis (Mtb) with antimicrobial activity and low toxicity that interferes with methionine metabolism processes and can be used to study tuberculosis.		Antibiotic
T3582	BTZ043		Antibacterial , Antibiotic , DprE1
	BTZ043 is a DprE1 inhibitor with nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro.		Antibacterial , Antibiotic , DprE1
T13346L	WQ3810 TFA	WQ3810 TFA(888032-58-4 Free base),KPI-10 TFA	Antifungal
	WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of Mycobacterium leprae resistant to ofloxacin.		Antifungal
T1940	BTB06584		RAAS , ATPase
	BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).		RAAS , ATPase
T0020	Sodium 4-aminosalicylate dihydrate	Sodium 4-Aminosalicylate,4-Amino-salicylic acid sodium salt	Free radical scavengers , NF-κB , Antibacterial , Antibiotic
	Sodium 4-aminosalicylate dihydrate (4-Amino-salicylic acid sodium salt) is the sodium salt form of aminosalicylic acid, an analog of para-aminobenzoic acid (PABA) with antitubercular activity. Sodium 4-aminosalicylate di...
T12231	NITD-349		Others , Antibacterial
	NITD-349 is an inhibitor of MmpL3. It shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv.		Others , Antibacterial
T21023	Bedaquiline fumarate	TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323	Antibacterial , Antibiotic
	Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. ...		Antibacterial , Antibiotic
T60877	Mtb ATP synthase-IN-1
	Mtb ATP synthase-IN-1 (compound 6ab) can be used in anti-mycobacterium research. Mtb ATP synthase-IN-1 shoys low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability that has good metabolic stability....
T67765	MenA-IN-2		Others
	MenA-IN-2 is a potent 1, 4-dihydroxy-2-naphthoate isopentadiene transferase (MenA) inhibitor with an IC50 value of 22 µM for MenA and 10 µM for Mycobacterium tuberculosis (Mtb). The continuous transmission of MenA-IN-2 M...		Others
T63056	Dovramilast	CC-11050	PDE
	Dovramilast (CC-11050) is an orally active phosphodiesterase 4 (PDE4) inhibitor that reduces the production of pro-inflammatory mediators and cytokines.Dovramilast is used in the study of Mycobacterium tuberculosis infec...		PDE
T7877	Thiacetazone	Diazam,Thioacetazone,Neustab,Neotibil	Others , Antibacterial , Antibiotic
	Thiacetazone (Diazam) is a thiosemicarbazone that thioacetazone treatment of pulmonary tuberculosis		Others , Antibacterial , Antibiotic
T5400	Q203	IAP6,Telacebec	Antibacterial , Antibiotic
	Q203 (Telacebec) is a novel potent anti-tuberculosis agent targeting cytochrome b subunit qcrB and inhibits M. tuberculosis H37Rv (MIC50: 2.7 nM).		Antibacterial , Antibiotic
T40520	Thiophene-2	Thiophene-2,TP2
	Thiophene-2 (TP2) is a targeted inhibitor of polyketide synthase 13 (Pks13), specifically designed to disrupt mycolic acid biosynthesis. By doing so, it effectively induces rapid cell death in mycobacteria. Thiophene-2 d...
T11817	Lansoprazole Sulfide D4		Proton pump
	Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.La...		Proton pump
T27477	GSK366A
	GSK366A is an anti-TB agent against Mycobacterium bovis BCG and Mycobacterium tuberculosis, targeting MmpL3 and inhibiting EchA6.
T25468	GSK1829820A	GSK-1829820-A,GSK 1829820A,GSK 1829820 A,GSK-1829820A
	GSK1829820A is a Mycobacterium tuberculosis H37Rv non-cytotoxic inhibitor.
T29701	AG 85	AG85,AG-85
	AG 85 is a major secretion protein of Mycobacterium tuberculosis.
T34177	Pseudopterosin E
	Pseudopterosin E can act towards Mycobacterium tuberculosis and other pathogens.
T31688	Ethambutol, (R,R)-	L-Ethambutol
	Ethambutol, (R, R)- can be used to treat tuberculosis. It is usually used in combination with other tuberculosis medications. It may also be used to treat Mycobacterium avium complex, and Mycobacterium kansasii.
T24397	ZTB23(R)	ZTB 23(R),ZTB-23(R)
	ZTB23(R) is the first potent and selective inhibitor of Mycobacterium tuberculosis Zmp1.
T11594	I2906		Others
	I2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis.		Others
T71727	HC102A
	HC102A is an inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence.
T61096	Antibacterial agent 95
	Antibacterial agent 95 (2-(quinoline-4-methoxy) acetamide), a new antituberculotic agent, exhibited a minimum inhibitory concentration (MIC) of only 0.3 μM against the reference strain of Mycobacterium tuberculosis H37Rv...
T11983	MDRTB-IN-1		Others
	MDRTB-IN-1 (5aα) is an antibiotic which is against Mycobacterium tuberculosis H37Rv(MIC90 :10.5 μM).		Others
T24765	SB-790594-A	SB790594A,SB 790594 A
	SB-790594-A is a non-cytotoxic Mycobacterium tuberculosis H37Rv inhibitor.
T24933	VCC234718	VCC-234718,VCC 234718
	VCC234718 is an IMPDH inhibitor. VCC234718 showed growth inhibitory activity against Mycobacterium tuberculosis. VCC234718 inhibits Mtb GuaB2 (Ki: 100 nM).
T69470	HC103A
	HC103A is an inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence.
T29527	ABT-255	ABT 255,ABT255,UNII-YA04O24J4T
	ABT-255 is a novel 2-pyridone antimicrobial agent for the treatment of tuberculosis. Both drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis showed efficacy in vitro and in vivo.
T70671	IC2418
	IC2418 is an MmpL3 inhibitor, being active against drug-resistant Mycobacterium tuberculosis.
T12121	MtbHU-IN-1		Others
	MtbHU-IN-1 is a Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU)inhibitor(binding to WT MtbHU with a Kd of 98 nM).		Others
T20799	Lobenzarit	Lobenzaritum
	Lobenzarit, an immunomodulator, is most frequently used to treat arthritis. Its chemical scaffold has been repurposed to tryptophan biosynthesis in Mycobacterium tuberculosis
T27848	LP10	LP-10,LP 10
	LP10 is a reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1 and a Potent type II inhibitor of Trypanosoma cruzi CYP51.

Compounds

Dup-721

T38359

Synonym:

Target: Antibacterial

BM212

T7342

Synonym:

Target: Antibacterial

AU1235

T10411

Synonym:

Target: Antibacterial

Target: Antibacterial, Antibiotic

TCA1

T5315

Synonym: TCA-1,TCA 1

Target: Antibacterial, Antibiotic

Cefsulodin sodium

T0827

Synonym: Cefsulodine sodium,Sulcephalosporin

Target: Antibacterial, Antibiotic

Target: Antibacterial

Antimycobacterial agent-4

T60073

Synonym: 4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide

Target: Antibacterial

GSK2556286

T9830

Synonym: GSK286

Target: Antibacterial

InhA-IN-4

T61411

Synonym:

Target: Antibacterial

Methyl quinoline-2-carboxylate

T77683

Synonym: Methyl 2-quinolinecarboxylate

Target: Antibacterial

InhA-IN-3

T60866

Synonym:

Target: Antibacterial

GSK1733953A

T27453

Synonym: DG70

Target: Antibacterial

TBA-354

T3642

Synonym: TBA 354

Target: Antibacterial, Antibiotic

Synonym: R207910,TMC207

Target: Antibacterial, Antibiotic

Target: Antibacterial, Antibiotic, DprE1

WQ3810 TFA

T13346L

Synonym: WQ3810 TFA(888032-58-4 Free base),KPI-10 TFA

Sodium 4-aminosalicylate dihydrate

T0020

Synonym: Sodium 4-Aminosalicylate,4-Amino-salicylic acid sodium salt

Target: Free radical scavengers, NF-κB, Antibacterial, Antibiotic

NITD-349

T12231

Synonym:

Target: Others, Antibacterial

Bedaquiline fumarate

T21023

Synonym: TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323

Target: Antibacterial, Antibiotic

Mtb ATP synthase-IN-1

Synonym: Diazam,Thioacetazone,Neustab,Neotibil

Target: Others, Antibacterial, Antibiotic

Q203

T5400

Synonym: IAP6,Telacebec

Target: Antibacterial, Antibiotic

Thiophene-2

T40520

Synonym: Thiophene-2,TP2

Target:

Lansoprazole Sulfide D4

Synonym: GSK-1829820-A,GSK 1829820A,GSK 1829820 A,GSK-1829820A

Synonym: L-Ethambutol

Target:

ZTB23(R)

T24397

Synonym: ZTB 23(R),ZTB-23(R)

Antibacterial agent 95

Synonym: SB790594A,SB 790594 A

Target:

VCC234718

T24933

Synonym: VCC-234718,VCC 234718

Synonym: ABT 255,ABT255,UNII-YA04O24J4T

Synonym: Lobenzaritum

カタログ番号	製品名	別名	ターゲット
T1426	Pyrazinamide	Pyrazinoic acid amide,Pyrazinecarboxamide	Antibacterial , Antibiotic , Autophagy , Fatty Acid Synthase
	Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.
TN2279	Totarol	(+)-Totarol	Antibacterial , Antifection
			Antibacterial , Antifection
TN1466	Canthin-6-one	NSC 103003	Antifungal
	Canthin-6-one (NSC 103003)is an alkaloid isolated from Allium neapolitanum with antibacterial activity and inhibitory effect against Mycobacterium tuberculosis.		Antifungal
TN5503	Linaroside		Antibacterial
	Linaroside exhibited 30% inhibition for antimycobacterial activity against Mycobacterium tuberculosis, strain H(37)Rv at 6.25 microg mL(-1) concentration.		Antibacterial
T5041	Faropenem sodium		Antibacterial , Antibiotic
	Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis.It treatment of tuberculosis and community-acquired pneumonia.		Antibacterial , Antibiotic
T5722	Nevadensin	Pedunculin	Anti-infection , Antibacterial
	Nevadensin is an important herb-based constituent inhibiting estragole bioactivation. Nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat. It also exhibits inhibition acti...		Anti-infection , Antibacterial
TN3207	7,3′,4′-Tri-O-methyleriodictyol	7,3',4'-Tri-O-methyleriodictyol	Antioxidant , Antibiotic
	7,3′,4′-Tri-O-methyleriodictyol (7,3;,4;-Tri-O-methyleriodictyol) is an isolate from the methanolic extract of Pogostemon cablin that possesses antimicrobial, antioxidant, antitumor, and antiprotozoal activities and inhi...		Antioxidant , Antibiotic
TN2086	Piperlotine A		Antibacterial
	Piperlotine A is an alkaloid that can be extracted from Piperonyssinus rolfsii and has antiplatelet aggregation activity.Piperlotine A showed inhibition of Mycobacterium tuberculosis in an in vitro assay with a MIC value...		Antibacterial
TN1019	Beta-mangostin	β-Mangostin	Apoptosis , Antibacterial , Parasite
	Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo...		Apoptosis , Antibacterial , Parasite
T3S1612	Kuwanon G	Moracenin B,Kuwanone G	Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
	1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...
TN5648	Porson
	Porson exhibited anti-tubercular activity against Mycobacterium tuberculosis H37Rv in vitro and MICs values of 40.0 μg/mL.
TN5684	5,6-Desmethylenedioxy-5-methoxyaglalactone
	5,6-Desmethylenedioxy-5-methoxyaglalactone is cytotoxic to small cell lung cancer (NCI-H187) cell line. It has antimycobacterial activity against Mycobacterium tuberculosis H(37)Ra.
T75564	Pomolic acid 3-acetate
	Pomolic Acid 3-Acetate, an antitubercular compound, exhibits a minimum inhibitory concentration (MIC) of 32 μM against Mycobacterium tuberculosis H37Rv [1].
TN4944	Santamarine		Caspase
	Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. Santamarine and reynosin show bactericidal activity agai...		Caspase
TN4336	Isothymusin		Antifection
	Isothymusin( MIC= 200 microg/mL) exhibits inhibition activity against Mycobacterium tuberculosis. It ( IC50=7.7 microg/mL ) exhibits antioxidant activity against the radical scavenging ability of DPPH.		Antifection
TN5657	Goniotriol
	Goniotriol shows antimycobacterial activity against Mycobacterium tuberculosis (MIC =100 microg/mL). It exhibits antiplasmodial activity against Plasmodium falciparum (IC50=2.6 microg/mL). Goniotriol shows cytotoxicity a...
TN4953	Sativan		Antifection
	Sativan possesses a broad spectrum of antimicrobial activity against bacteria and phytopathogenic fungi, it exhibits antituberculosis activity against Mycobacterium tuberculosis H37Rv, with the MIC value of 50 ug/mL.		Antifection
TN3560	Cabralealactone		Antifection
	Cabralealactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line, it is moderately active against a small-cell lung cancer (NCI-H187) cell l...		Antifection
TN3557	Cabraleadiol		ATPase , Antifection
	Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol inhibits photosystem II (PS II) and induces the appearance ...		ATPase , Antifection
TN3559	Cabraleahydroxylactone		HSV
	Cabraleahydroxylactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line.It shows antiviral activity against herpes simplex virus type-1 with...		HSV
TN4776	Physalin D		TNF , Antifection
	Physalin D shows antimalarial activity; it also exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 microg/mL. Physalin D displays considerable cytotoxicity aga...		TNF , Antifection
TN3924	Eichlerialactone		Others
	Eichlerialactone and ethyl eichlerianoate show antimycobacterial activity against mycobacterium tuberculosis H37Ra, with minimum inhibitory concentration in the range of 25-50ug/mL; eichlerialactone exhibits good antibac...		Others
T75631	Ganorbiformin B
	Ganorbiformin B, a lanostane triterpenoid, belongs to the same structural class as ganoderic acids, sharing the lanostane skeleton. It is the C-3 epimer of ganoderic acid T, known for its potent antimycobacterial activit...
T75633	(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid
	(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid (compound 15) serves as an antitubercular agent, displaying a minimum inhibitory concentration (MIC) of 12.5 μg/mL against Mycobacterium tuberculosis H37Ra. A...
T72742	(-)-Pinocembrin
	(-)-Pinocembrin demonstrates anti-mycobacterial activity against Mycobacterium tuberculosis H37Ra, presenting IC 50 values of 1.11 mg/mL in the dormant phase and 1.21 mg/mL in the active phase. Additionally, this compoun...
TN5014	Shoreic acid		Antifection , HSV
	Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also shows antifungal activity against C. albi...		Antifection , HSV
TN1694	Gliotoxin		Apoptosis , NF-κB , Wnt/beta-catenin , COX , PKA , Antibacterial , Antifection
	Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway.
T38330	Collinin
	Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Col...
TN1378	α-Viniferin	ALPHA-VINIFERIN	P450 , NO Synthase , Prostaglandin Receptor
	α-Viniferin known as 2-arylbenzofuran flavonoids, that are inhibitors of prostaglandin H2 synthetase. α-Viniferin has anti-Alzheimer's disease, anti-tuberculosis, anti-tumor, anti-inflammation, anti-diabetes and other ph...		P450 , NO Synthase , Prostaglandin Receptor

天然物製品

Pyrazinamide

T1426

Synonym: Pyrazinoic acid amide,Pyrazinecarboxamide

Target: Antibacterial, Antibiotic, Autophagy, Fatty Acid Synthase

Totarol

TN2279

Synonym: (+)-Totarol

Target: Antibacterial, Antifection

Target: Antibacterial

Faropenem sodium

T5041

Synonym:

Target: Antibacterial, Antibiotic

Nevadensin

T5722

Synonym: Pedunculin

Target: Anti-infection, Antibacterial

7,3′,4′-Tri-O-methyleriodictyol

TN3207

Synonym: 7,3',4'-Tri-O-methyleriodictyol

Target: Antioxidant, Antibiotic

Piperlotine A

TN2086

Synonym:

Target: Antibacterial

Beta-mangostin

TN1019

Synonym: β-Mangostin

Target: Apoptosis, Antibacterial, Parasite

kuwanon G

T3S1612

Synonym: Moracenin B,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

5,6-Desmethylenedioxy-5-methoxyaglalactone

TN5684

Synonym:

Target:

Pomolic acid 3-acetate

Target: ATPase, Antifection

Cabraleahydroxylactone

Target: TNF, Antifection

(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid

Target: Antifection, HSV

Gliotoxin

TN1694

Synonym:

Target: Apoptosis, NF-κB, Wnt/beta-catenin, COX, PKA, Antibacterial, Antifection

Synonym: ALPHA-VINIFERIN

Target: P450, NO Synthase, Prostaglandin Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-03022	PstP Protein, Mycobacterium tuberculosis, Recombinant	Mycobacterium tuberculosis	E. coli
	Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth an...
TMPH-03014	MPT63 Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	N/A. MPT63 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.7 kDa and the accession number is P9WIP0.
TMPH-03000	ATase Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. ATase Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis ta...
TMPH-03001	MT2731 Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	P. pastoris (Yeast)
	Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin MT2730. MT2731 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in yeast with N-6xHis tag. The pred...
TMPH-03010	EsxB Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	P. pastoris (Yeast)
	A secreted protein. Acts as a strong host T-cell antigen. Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm. Might serve as a chaperone to prevent uncontrolled membrane lysis...
TMPH-03006	Ag85B Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	P. pastoris (Yeast)
	Ag85B Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.7 kDa and the accession number is P9WQP0.
TMPH-03007	Ag85C Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	Ag85C Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.1 kDa and the accession number is P9WQN8.
TMPH-03021	PstP Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth an...
TMPH-03016	MPT64 Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	P. pastoris (Yeast)
	MPT64 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in Yeast.
TMPH-03008	ENR Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	ENR Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.6 kDa and the accession number is P9WGR0.
TMPH-03004	Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.1 kDa and the accession number is P9WQP2.
TMPH-03018	MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requ...
TMPH-02999	UL2 Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase acti...
TMPH-03612	SodC Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)	Mycobacterium tuberculosis	E. coli
	Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes. SodC Protein, Mycobacterium tuberculosis, Recomb...
TMPH-03003	Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)	Mycobacterium tuberculosis	E. coli
	Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.6 kDa and the accession number is P9WQP2.
TMPH-02409	LprG Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)	Mycobacterium tuberculosis	E. coli
	LprG Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.2 kDa and the accession number is P9WK44.
TMPH-03196	PYCR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)	Mycobacterium tuberculosis	E. coli
	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. PYCR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predic...
TMPH-03017	CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)	Mycobacterium tuberculosis	Baculovirus Insect Cells
	Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethy...
TMPH-03002	FtsQ Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)	Mycobacterium tuberculosis	E. coli
	Essential cell division protein. FtsQ Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.2 kDa and the...
TMPH-03019	MPT51 Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)	Mycobacterium tuberculosis	E. coli
	May have a role in host tissue attachment, whereby ligands may include the serum protein fibronectin and small sugars. MPT51 Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) is expressed in E. coli expressio...
TMPH-03012	HBHA Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)	Mycobacterium tuberculosis	E. coli
	Required for extrapulmonary dissemination. Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells. HBHA Protein, Mycobacterium tuberculosis, Recombinant (His &...
TMPH-03011	EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)	Mycobacterium tuberculosis	E. coli
	EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth fact...
TMPH-00758	EspK Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)	Mycobacterium tuberculosis	E. coli
	May act as a chaperone that facilitates EspB secretion through an interaction with EccCb1.
TMPH-03005	Ag85B Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His)	Mycobacterium tuberculosis	E. coli
	Ag85B Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.2 kDa and the accession number is P9WQP0.
TMPH-03009	EsxB Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His)	Mycobacterium tuberculosis	E. coli
	A secreted protein. Acts as a strong host T-cell antigen. Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm. Might serve as a chaperone to prevent uncontrolled membrane lysis...
TMPH-03015	MPT64 Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His)	Mycobacterium tuberculosis	E. coli
	N/A. MPT64 Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is P9WIN9.
TMPH-03013	HRP1 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)	Mycobacterium tuberculosis	E. coli
	Unlike some other CBS-domain containing proteins does not seem to bind AMP.
TMPH-03023	AmiB2 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)	Mycobacterium tuberculosis	E. coli
	AmiB2 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-03020	MTR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)	Mycobacterium tuberculosis	E. coli
	Catalyzes the NAD(P)H-dependent reduction of mycothione (the oxidized disulfide form of mycothiol) to mycothiol.
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His)	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...